Graphpad prism and/or excel can do many of the calculations. I use Phoenix. It is ideal but expensive. Here's a link to a comprehensive list that might be helpful. http://www.boomer.org/pkin/soft.html

I Use R + Rstudio (GPL) software for NLS and noncompartmental analysis, it can also perform NLME, BA/BE study .

See here for more info on R + PK : http://cran.r-project.org/web/views/Pharmacokinetics.html

Thanku so much sir.

hello ashvini; good to see u on research gate. R is open access software. other options are phoenix and kinetica but they are not open access. we are explorig right now kinetica at our place. wat is your exact application.

I agree with Nirmal, WinNonlin is a good option and it is user friendly but it has limited applications in the free version (certain functions can not be performed) and the licensed one is expensive which is usually bought by the universities, research institutes and companies!

Go for GraphPad Prism............But Best is Origin Pro 8 software.

Dear Ashvini D Soni ,

New JAVA based commercial PK software is available here: www.thothpro.com

Best regards,

Tomasz

Thanks a lot for all sugestions about PK softwares...