What is the best way for synthesis of 2',4-dihydroxychalcone?

I'm trying to synthesize 2',4-dihydroxychalcone using 2-hydroxyacetophenone and 4-hydroxybenzaldehyde. I've done several sythesis but all I get was some kind of oil and no precipitate of product...

03 April 2019 6,167 4 View

Can you use a t-test instead of an ANOVA in a multi-factorial design if you're interested in only one comparison?

25 February 2019 9,243 4 View

Does HRV-3C protease cleave TEV cleavage site?

I have heard some rumors that the HRV-3C protease can recognize and cleave ENLYFQG peptide, which is a consensus sequence cleaved by the TEV protease. Can anyone confirm or suggest some literature...

23 July 2018 1,321 4 View

Are there any wide-spectrum kinase inhibitors?

I wanted to analyze the phosphorylation of a certain mammalian protein. It is a standard procedure to add phosphatase inhibitors to extraction buffers to block the process of dephopshorylation....

12 March 2018 8,978 4 View

What book/article would be a good introduction into artificial neural networks?

Hi, I'd like to learn more about artificial neural networks, specifically pattern recognition algorithms. Unfortunately, I don't have much of a background in mathematics, so I'm looking for...

26 December 2017 4,850 2 View

Best tool for generating topology of polymer brushes (MD)?

17 September 2017 7,160 1 View

What is the resolution of ion-exchange chromatography?

Dear all, I would like to ask what is the maximal achievable resolution of ion exchange chromatography in the matter of pI values. In particular I am wondering whether I will be able to separate...

11 October 2016 5,605 3 View

Software for load path optimized structural design of fiber reinforced materials?

Which software would be most suitable for carrying out a load path analysis of an existing part, such as an aircraft wing structure, and subsequently doing a topology optimization of that design...

09 August 2016 874 1 View

What are the best 3 different reporter proteins as fusion partners for structural studies?

07 July 2016 5,040 2 View

Which one of databases do you recommend to explore validated targets for miRNA categorized by disease/metabolic disorder?

24 November 2014 8,772 2 View

Irradiation data for JAPAN?

Hi, Could you help me to get the latest (2019, 2020) solar resource data for a particular site in JAPAN? PV GIS and NSRDB data are not in reach to JAPAN, I'm looking for some other database for...

03 March 2021 961 3 View

Why are the velocities so high in my Boussinesq approximation Fluent simulation?

Hello, I have a mechanism where air rises due to convective flows. In this simulation, nothing is driving the air except this. I understand that the Boussinesq approximation only works for small...

02 March 2021 4,910 3 View

How to calculate BREQ 3 questionnaire?

how to calculate BEHAVIOURAL REGULATION IN EXERCISE QUESTIONNAIRE BREQ 3 ,which contain 24 questions and each question has 5 answers (0- Strongly disagree , 1-disagree, 2- Neither agree nor...

02 March 2021 811 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Please suggest a good text book for "Research Methodology in Life Sciences". Which book would be good for PhD Scholars?

Please provide Book Title and author name

02 March 2021 9,059 3 View

Could any one guide me, to write research proposal for grant? ?

We have one plant, the local people using this for controlling blood sugar, the toxicity and antidiabetic activity of the plant is not reported yet, please guide from whag should be the process ?...

02 March 2021 2,300 1 View

Is anyone familiar with the cyclic compressive fatigue testing (BS EN 12697 - 25) ?

I would like to get more information on the cyclic compressive fatigue testing (BS EN 12697 - 25) which is typically done for bituminous material in pavement design. Any one can advise on the...

28 February 2021 2,004 3 View

What is Flat Lens Antenna?

28 February 2021 5,433 3 View

Can impedance of antenna be less than 50 ohms?

I am simulating helix antenna in hfss, right now, giving excitation with 50 ohms port. When I see the results of Z parameter (real). It shows lower than 50 ohms. Do not understand, if it can be...

27 February 2021 4,218 7 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View