Does anyone know if a comparison of gene expression profiles has been performed for human breast cancer tumor, healthy surrounding tissue, as well as post-treatment? Either chemotherapy or targeted? I have found datasets from needle biopsies comparing the tumor to minimal residual disease but without the the histologically healthy surrounding tissue.
Dear Kristina,
Maybe you can find some data to work on your subject with these GEO series ID : GSE9574, GSE10797, GSE20437.
Data (from Affymetrix arrays) are available.
Go to www.ncbi.nlm.nih.gov/geo/
Best regards
Thank you, Wilfried, I have indeed already seen GSE9574 and GSE20437. My difficulty is in obtaining datasets including, normal, diseased, and post-treatment, as I am interested in understanding how the cells which survive treatment differ from the healthy surrounding tissue, both the epithelial and stromal components. A bit of a tough one I am afraid.
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