If you mean RT-PCR, a positive test result for SARS-CoV-2 infection can be obtained with a throat swab in the first week of infection. If the case is suspected to have had the infection for a least a week, i.e. they are in the second week following the infection, pulmonary discharges, e.g. sputum, is preferred, as the virus can no longer be detected in throat in this time period.
It depends on the particular test. PCR tests detect active infections, they are highly specific and the sensitivity varies depending on how well the biochemistry is optimized. See here:
Article Variation in False-Negative Rate of Reverse Transcriptase Po...
Serological tests (antibodies or antigens) do not necessarily detect active infections but also previous episodes. They are much less specific than PCR tests.
Normally, on average it takes 5–6 days from when someone being infected with the virus for symptoms of the COVID-19 to appear, however it can take up to 14 days. The minimum time required for detection of patient after infected with virus is depends on the particular test. In case of RT-PCR, a positive test result for COVID-19 infection can be obtained in the very first week of infection.
Although RT-PCR test for COVID-19 on nasopharyngeal or oropharyngeal swabs usually is positive by 5th day of the illness, the positivity of the test depends on the quality of the sampling technique as well as by the sensitivity of the test kit. Therefore, in a patient with suggestive symptoms of COVID-19, if negative initially RT-PCR result may become positive on repeated testing on 6- days of the illness.
Hope there articles can illuminate you about this topic:
1. Article Real-time RT-PCR in COVID-19 detection: issues affecting the results
2. Article Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT?
3. Preprint Diagnosis of Coronavirus Disease 2019 (COVID-19): Neither Ch...
It depends on the specific test. PCR tests detect active infections, they are very specific, and sensitivity varies depending on how well biochemistry is optimized. Normally determine the virus for 5-6 days. Test systems in China more accurate begin to determine on day 2 of infection. In Russia, the test systems of the "Vector" Corporation give a positive result from the first days of infection. Regards, Sergey Viktorovich Pushkin
RT-PCR is the best method to diagnose an acute COVID-19 infection. specific antibodies Determined using serological tests are applied to check the abundance and period prevalence of the disease, but does not show active infection.
When the test for covid 19 become positive after infection of virus ,the development of immunity to a pathogen through natural infection is a multi-step process that typically takes place over 1-2 weeks.the body responds to a viral infection immediately with a non specific innate response in which macrophages ,neutrophils and dendritic cells glow the progress of virus and many even prevent it from causing symptoms.this non specific response is followed by an by an adaptive response where the body makes antibodies that specifically bind the virus.those antibodies are proteins called immunoglobulins.the body also makes T-cells that recognize and eliminate other cells infected with cells infected with the virus,this is called cellular immunity .this combined adaptive response may clear the virus from the body,and if the response is strong enough may prevent progression to severe illness or reinfection by the same virus.this process is often measured by the presence of antibodies in blood .
Who continues to review the evidence on antibody responses to SARS-cov 2 infection.most of these studies show that people who have recovered from infection have antibodies to the virus.However ,some of these people have very low levels of neutralizing antibidies in their blood ,suggesting that cellular immunity may also be critical for recovery .As of 24 April 2020 no study has evaluated whether the presence of antibodies to Sars cov2 confers immunity to sebsquent infection by the virus in humans.
Laboratory tests that detect antibodies to sars cov 2 in people including rapid immuno diagnostic tests,need further validation to determine their accuracy and reliability.inaccurate immunodiagnostic tests may falsely categorize people in 2 ways the first is that they may falsely label people who have been infected as a negative and the second is that people who have not been infected are falsely labelled as positive both errors have a serious consequences and will affect control efforts .these tests also need to accurately distinguished between past infections from sars cov2 and those caused by the known set of six human coronavirus.four of these viruses causes the common cold and circulate widely.
These studies will provide data on the percentage of people with detectable covid 19 antibodies ,but most are not designed to determine whether those are immune to secondary infections,there is not enough evidence about the effectiveness of antibodies mediated immunity to guarantee the accuracy of an "immunity passport "or "risk free certificate .people who assume that they are immune to a secondary infection because they have received a positive test result may ignore public health advise.
A mayor factor is that african population is much younger - 41% below 15 years means the virus will spread not as fast and only 3% 65 and older (Italy for instance is well over 20%) may get the case-fatality-rate down. Of course extremly low levels of testing are also a mayor factor for the numbers.
The virus becomes detectable after 5-14 days. The incubation period is quite long. There are different test systems. But this, as a rule, does not allow to detect the virus, for example, for 1 day of infection. Regards, Sergey Viktorovich Pushkin
It is very difficult to predict for an assymtomatic pateints who are actively spreading infections . The nature of Covid mutation also plays a role between
Lag ( Inactive ) to Exponential Phase ( Symptomatic Covid pateints ).
Patient will start having symptoms with covid 19 between 2-14 days,this symotoms appears after exposure,the symptoms include tiredness,sore throat,headache,diarrhea,chills,cough,muscles ache,body pain etc