If the genome contains the gene and primers can hybridize then yes.
If you get negative results you should check primer sequences, optimise PCR parameters such as annealing temperature. You may supplement buffer with DMSO and/or magnesium if necessary.
There is no such gene specific universal rule to get always positive result. It is solely depends on the primers and other reaction parameters. If you are not getting the positive result, check the parameters as Laczi mentioned. It would be easier to troubleshoot, if you share more information about your experiment.