Hi! I have to write a proposal for my research class and I'm a little confused. I'm considering proposing a study that would require a comparison between a select group of patients KT/V lab values before an intervention and KT/V values after an intervention. I'm looking to determine if values stay the same or decrease after the intervention. What kind of study design would this be considered and what would be the proper way to analyze the data statistically? I would appreciate any guidance you can offer!
Dear Michelle
If the data are for the same group of patients and the number of patients is grater than 30, you can use paired sample T test. But if the number of patients is less than 30, you can use non-parametric T test.
Regards,
Zuhair
Thank you! It would be less than 30. I'm struggling with the design as well. At first I thought it was a bioequivalence trial in that it matches that description in almost every way except for the fact that I'm not looking to test a pharmaceutical but a treatment delivery that produced the same results as the previous treatment method. In other words I am trying to show that either method is acceptable. Would this fit into a Bioequivalence design? Or am I way off with that thought? Thanks again for you help!!
Or maybe I would just use a quasi experimental, one group, pre test -post test design? I'm leaning this way but want to be sure I am correct. I cant seem to move on with my work until I can figure this part out!!
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