Mycotoxins are toxin substances produced by fungi or molds. The major mycotoxins are: Aflotoxins, AFB1 etc. Aflotoxins may be degraded by the fungi Aspergillus species ( Mishra and Das, 2003; Wu et al. 2009). It can also be metabolized by certain species of actinomycetes such as Nocardia asteroids, Rhodococcus erythropolis etc. Laccase enzyme can degrade AFB1 (Alberts et al. 2009). The bio-factors that supports detoxification are: Available nutrients, Lipoic acid concentration, Oxygenating and conjugatic plant enzymes, Presence of active enzymes like phytase etc.
Mycotoxins are toxin substances produced by fungi or molds. The major mycotoxins are: Aflotoxins, AFB1 etc. Aflotoxins may be degraded by the fungi Aspergillus species ( Mishra and Das, 2003; Wu et al. 2009). It can also be metabolized by certain species of actinomycetes such as Nocardia asteroids, Rhodococcus erythropolis etc. Laccase enzyme can degrade AFB1 (Alberts et al. 2009). The bio-factors that supports detoxification are: Available nutrients, Lipoic acid concentration, Oxygenating and conjugatic plant enzymes, Presence of active enzymes like phytase etc.
Mycotoxin metabolism is complex and involves pathways of bio-activation and detoxification in both humans and animals. Detoxification occurs via transformation mediated by enzymes in the host cells and in the digestive microbial flora. Some of the toxins and their metabolites may become fixed to animal or human tissues. However most are eliminate in the urine, feaces and milk. For details consult Asian Journal of Animal Sciences Vol 2 ( 1 ): 7 - 25, 2008