I am interested in studying the natural mechanisms that change the appearance of the prostate under conditions of high pressure including herniation through the bladder neck and anteroposterior axis elongation.
It is possible that increased pressure to the prostate induces production of the CYP7B1 and thus increases the production of 7alpha hydroxylated steroids (such an increase was shown in cell cultures (Akwa Y. et al. 1986 or 1987). The produced 7alpha-hydroxysteroids are in turn transformed into 7beta-hydroxy derivaives by the 11beta-HSD1. Such 7beta-hydroxysteroids have cell regenerating properties as shown in several of my (Morfin) late publications.
There is an ultrasound technique called shear-wave elastography (SWE) performed by means of transrectal ultrasound. It can quantify the pressures and show color scale together with accurate measurement of pressure. There is only one ultrasound machine capable of SWE, its is Aixplorer, manufactured actually by French company, Supersonic Imagine, Aix-en-Provence.
Best PM.