What will be the efficient route for synthesis of 2-hydroxy-5-nitroisophthalaldehyde??

Maheshkumar Prajapati @Maheshkumar-Prajapati

07 July 2023 0 3K Report

I found difficulty in synthesizing of 2-hydroxy-5-nitroisophthalaldehyde from p-nitrophenol by using duff reaction(HMTA, Trifloroacetic acid at 110 oC) having yield around 4-6 %

please provide ortho- diformylation of p-nitrophenol. Is there any other condition to apply for it?

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