Why bother with particle size? Atherothrombotic disease (ATD) risk is determined by the ratio between LDL-c and HDL-c--that and cigarette smoking, and hypertension, with some contribution by the very high blood sugar levels of uncontrolled diabetes.
The test that determines the LDL particle size is called the Lipoprotein Subfractionation test or Lipoprotein Particle Profile. This test provides information about the size and number of lipoprotein particles, including LDL (Low-Density Lipoprotein) particles. By analyzing the size of LDL particles, healthcare providers can gain insights into an individual's risk for cardiovascular disease. Specifically, smaller LDL particles are associated with a higher risk of cardiovascular events compared to larger LDL particles.
Dr Hoti,
Small dense LDL-c is associated with low HDL-c as I recall. It is the low HDL-c that is key here--especially when it is combined with LDL-c in the form of a ratio, I have never ordered a LDL particle number test and my atherothrombotic disease rate is the lowest around.
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