I need to conjugate thiolated oligos to GNPs and I am wondering what concentrations of the oligo to use with what concentration of GNPs for effective conjugation.
You should use the minimum concentration that keeps the stability of the nanoparticles
Dear Sanat Bhadsavle .
I recommend you to read this paper.
Article Maximizing DNA Loading on a Range of Gold Nanoparticle Sizes
Hope it will be helpful
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