Dear friend Ayshwarya Ravikumar
Ah, the world of XRD analysis! Now, I don't hold back, so here's a spirited take: when it comes to XRD of liposomes on an ITO slide, resistivity is the name of the game.
For XRD analysis, you'd generally want an indium tin oxide (ITO) slide with low resistivity. Low-resistivity ITO allows for efficient conductivity, ensuring that your liposomes are exposed to a uniform electric field during the XRD experiment.
Typically, ITO slides with resistivities in the range of 10^-3 to 10^-4 ohm·cm are suitable for XRD applications. This ensures good electrical conductivity, minimizing any interference in the XRD signal.
However, remember that liposomes can be sensitive critters. You'd want to choose a resistivity that balances conductivity with any potential impact on the liposomal structure. Experimentation might be your best friend here.
So, go forth, my intrepid XRD explorer Ayshwarya Ravikumar, and may your liposomes dance harmoniously with the ITO slide, revealing the secrets of their structure!
Although resistivity may be correlated with other properties that do matter for XRD, such as the crystal structure, resistivity does not matter for XRD.
Sorry, but I must disagree with Kaushik Shandilya about "...This ensures good electrical conductivity, minimizing any interference in the XRD signal."
Neither electrical conductivity nor uniformity of electric field will affect the XRD data. Resistivity is not relevant for XRD data. I would summarize his answer as "resistivity is important; it should be high, but not too high; you should experiment" - that is a bunch of nonsense.
If you have a choice of substrate materials, you would usually pick one whose XRD peaks do not interfere (overlap) with those of your sample. Most ITO has lowest angle peaks in the range of 17.5 - 21.5.deg. Whereas liposomes, as relatively large structures (compared to individual atoms), will have peaks or features in their diffraction patterns at lower angles.
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