How does Anti-retroviral therapy effect cryptococcal meningitis?

I have read that early administration of ART in cases effected with cryptococcal meningitis lead to a higher level of mortality but unfortunately could not get a clear understanding about the...

31 December 2018 7,040 0 View

I am working on a natural compound which is active against cryptococcous hving an MIC around 5.5 mg/ml. Can it be considered as an antifungal?

I am working on a natural compound which is active against cryptococcous hving an MIC around 5.5 mg/ml. Can it be considered as an antifungal or a potent antifungal drug candidate? Is there any...

13 October 2018 7,718 3 View

I am working on a natural compound which is active against cryptococcous hving an MIC around 5.5 mg/ml. Can it be considered as an antifungal?

I am working on a natural compound which is active against cryptococcous hving an MIC around 5.5 mg/ml. Can it be considered as an antifungal or a potent antifungal drug candidate? Is there any...

09 October 2018 9,955 4 View

Need a protocol for PI and Dapi staining to identify dead cells for confocal microscopy?

I am looking for a protocol to stain yeast cells with PI and DAPI in order to identify dead cells with confocal microscopy.

10 August 2018 2,365 1 View

Need a protocol for PI and Dapi staining to identify dead cells for confocal microscopy?

I am looking for a protocol to stain yeast cells with PI and DAPI in order to identify dead cells with confocal microscopy.

07 August 2018 4,631 1 View

How to decide an antimicrobial's concentrations to be used to check susceptibilities if it has not yet been used against the organism of interest?

I am testing plant product against a yeast and want to determine the minimum inhibitory concentration of the same against the fungi. It has not yet been used against the said yeast. What...

06 July 2018 1,111 1 View

Can any one tell me about efficient fluorescent plasma membrane markers for yeast cell?

I want to visualize the effect of a drug on the plasma membrane of the yeast cell. What are the fluorescent markers that I can employ for this?

01 February 2018 4,937 2 View

I need to install GROMACS on windows 10, 64 bit system. Can anyone help me with a step by step tutorial?

08 September 2017 1,011 16 View

What is the most feasible method for protein sequencing and where in India can it be done?

Protein sequencing

09 October 2015 7,838 0 View

Why are Minimum inhibitory concentration indicated as MIC 50 or MIC 80 or some times MIC 90?

Which one should be determined and what is the basis of selection? Minimum inhibitory concentration against fungi

05 June 2015 9,011 23 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Does any one can help me choose a reasonable basis set for intermediate metal ions interactions with guanine (i.e Fe2+, Mn2+, Cu2+ and exc.)?

Hello every body Does any one has any idea to help me choose a reasonable basis set for intermediate metal ions (i.e Fe2+, Mn2+, Cu2+ and exc.) interactions with guanine or other DNA organic...

01 March 2021 6,187 2 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

Is there a deep reason for using the squared modulus of the wave function as the probability density of the existence of the particle?

I think we were all surprised at the first time we got to know quantum mechanics that the squared modulus of the wave function is the probability density of the existence of the particle? The role...

28 February 2021 6,282 9 View

Why does intensity drops as concentration increases?

Is there any reason for decrease in fluorescence emission intensity of HSA,BSA when increase the concentration ?

28 February 2021 3,653 4 View

POlymer+DMSO solution and moisture??

What could be the reason of moisture at the sides of Vial when I am preparing my polmyer+DMSO solution for membrane fabrication? What etiquettes I am possibly missing here?

28 February 2021 6,516 5 View

Should we reduce the standard unit of length to 0.31951540592 meter ?

The reasoning behind this question is to align the ratios of the proton potential in energy per charge to the speed of light in distance per time. As these two dimensions appear to be related,...

27 February 2021 947 7 View

What could be reason for getting such type of graph for complex impedance in case of polymer blend films?

Its effect appears in real part of ac conductivity also. Can anyone suggest any reason behind it?

26 February 2021 3,487 3 View

How to plot the probability paper of Gumbel distribution using R programing?

In R-studio, there are many commands of Gumbel package. Arguments are also different. I`m asking about the alpha parameter of the Copula which must be greater than 1. If this is the one used to...

25 February 2021 5,229 3 View