Dear Manal Hadi Kanaan According to an expert, the new variant is showing some 17 changes in the genome, which is a very large change. Due to this change, the transmissibility of this virus has also changed, and is 70% more infectious compared to the earlier variant. The details can be accessed at the link given below:

https://www.indiatoday.in/coronavirus-outbreak/story/expert-explains-why-uk-s-more-infectious-covid-19-strain-spreads-faster-1751487-2020-12-21

Regards!

Dear Manal Hadi Kanaan According to an expert, the new variant is showing some 17 changes in the genome, which is a very large change. Due to this change, the transmissibility of this virus has also changed, and is 70% more infectious compared to the earlier variant. The details can be accessed at the link given below:

https://www.indiatoday.in/coronavirus-outbreak/story/expert-explains-why-uk-s-more-infectious-covid-19-strain-spreads-faster-1751487-2020-12-21

Regards!

Dear Dr Manal Hadi Kanaan , Yes this is a very serious issue. I endorse the views of Dr Arbind K. Choudhary. Many experts pointed out that the new variant (virus) is spreading fast infecting more people in UK. It might have already spread to other countries. But, many scientist points out that the there is no increase in mortality rate that can be attributed to this new strain. But, surely I am little worried about economy/people. Warm regards Yoganandan G

Let's we watch ....as investigated its spike protein .is more dangerous which makes it more vulnerable and spreading in nature

Thanks a lot Dr. Arbind K. Choudhary really thanks. I fully agree with you The new variant carries a mutation called "N501Y" in the "spiny" protein of the Coronavirus, which is present on its surface and allows it to adhere to human cells to penetrate it. According to Dr. Julian Tang of the University of Leicester, "This variant was spreading intermittently earlier this year outside the United Kingdom, in Australia between June and July, the United States in July, and in Brazil in April." My sincere gratitude, Doctor.

Thanks a lot Dr. Yoganandan G. really thanks. I fully agree with you in concern about the economy and people, and we also hope that the vaccine will actually be effective against this strain as well, as Professor Julian Hescox of the University of Liverpool pointed out that “Coronaviruses mutate all the time and therefore it is not surprising that new variants of SARS-Cove have appeared. The most important thing is to know whether this strain has characteristics that would affect human health, diagnoses, and vaccinations. My sincere gratitude, Doctor.

Thanks a lot Dr. M.K. Tripathi really thanks. I fully agree with you the new variant carries a mutation called "N501Y" in the "spiny" protein of the Coronavirus, which is present on its surface and allows it to more vulnerable and spread in nature. My sincere gratitude, Doctor.

It is spreading widely and rapidly. We hope that it will be contained.

Thanks to all .

In fact huminity is passing through real fear...

Thanks a lot Dr. Hassan Izzeddin Sarsak really thanks. I fully agree with you the new variant spread very quickly, we hope it actually contains, God protects us. My sincere gratitude, Doctor.

I fully agree with you Dr. M.K. Tripathi Humanity faces real fear, but unfortunately in my country, the fear that we face is not represented by this virus only, but there is something much more dangerous than it. My sincere gratitude doctor.

Yes madam I do agree ..

In fact ..

Even after we all have so much knowledge education sense ..why be in hand of very few numbers of stupid peoples this is real subject of investigation and seems to be continued in 2050 as well...

I totally agree with you Dr. M.K. Tripathi, not for 2050, but maybe forever ... In our culture we say you've put your hand on the wound, Doctor.

Yes madam you said it..

Yes Dr. Manal Hadi Kanaan you and other colleagues said lot of the facts and expectations about this new variant of corona.. from my point of view the economic factors are presented strongly in this period of the virus 🦠 development.. Allah blesses all inshaAllah 🙏

Thanks a lot Dr. Ahmad A. Al Rababah really thanks. I fully agree with you about that. May Allah blesses us. My sincere gratitude doctor.

May Allah protect us from this virus.

I agreed to the statement delivered by Manual Hadi Kanaan that the new variant of Corona virus will be having more vigorous transmission than previous one.

Every one has to alert in their social, economic productive movements and lifestyle practices in routine life.

Certain blood group people are highly vulnerable to this new variant has many structure and shape in its action and transmission. The affected one must be isolated from the community to save the others also. We have read the previous century history of spine flu attack on 1917 to 1920.

All God's will save the world population due to the invention of vaccination and medicine from different countries. Rest in the hands of God's.

Thanks a lot Dr. Mubashir Ali Rather really thanks, fully agree with you. May Allah blesses us. My sincere gratitude doctor.

Thanks a lot Dr. Senapathy Marisennayya really thanks, fully agree with you. Everyone should pay more attention and follow the health instructions carefully. May Allah blesses us. My sincere gratitude doctor.

Thank you for the link Arbind K. Choudhary

Thank you Dr.Manal Hadi Kanaan for your acknowledgement. Regards

Dear Dr Manal Hadi Kanaan, I wish to add one more point to the discussion. As appeared in newspaper:

BioNTech CEO says shots highly likely work on mutant variant, but adds that mRNA vaccine can be modified in 6 weeks to mimic the variant (if needed)- Source: Times of India ( 23.12.2020).

My observation is that eventhough the vaccines may be successful, a sudden spike in number of infected persons will overload the healthcare system. So, people need to be vigilant and continue following preventive measures until vaccination programmes cover every one. Warm regards Yoganandan G

I fully agree with you madam @ Manal Hadi Kanaan.

Dear Dr. Manal Hadi Kanaan you have perfectly said about the new variant of C-19 and it may the cause of the massive global epidemic. However, vaccinating already have started, peoples are well oriented about the preventive measures. Hopefully, the mercy of the Almighty Allah will safe the universe from this grievous situation.

Unfortunately, even the British government announces that new strain'S danger 💔

Thanks a lot Dr. Yoganandan G. really thanks. I fully agree with you that there is no indication at the present time that this new strain causes a high mortality rate or that it affects vaccines and treatments, but the increase in cases and the speed of spread will constitute a large and noticeable burden on the healthcare facilities and calls for adherence to health guidelines. My sincere gratitude doctor.

Thanks a lot Dr. Paramasivam Sivaraj really thanks.

Thanks a lot Dr. Md. Abdur Razzak Choudhury really thanks. I fully agree with you about that, always the will of the Almighty is above everything, we hope to save the universe from this pandemic soon. My sincere gratitude doctor.

Thanks a lot Dr. Diana A. Ali really thanks. The news circulated that it is faster spreading, on the other hand, we hope and hope that it will be less dangerous. My sincere gratitude, Doctor.

Dear Dr. Kanaan!

We need more time to gather data on this new variant of COVID-19:

1) da Silva Filipe, A., Shepherd, J.G., Williams, T. et al. Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland. Nat Microbiol 6, 112–122 (2021). Open Access:

https://www.nature.com/articles/s41564-020-00838-z

2) Michael G Baker et al. (2020). Elimination could be the optimal response strategy for covid-19 and other emerging pandemic diseases © 2020 BMJ Publishing Group Ltd 22 December 2020) Open Access:

https://www.bmj.com/content/371/bmj.m4907\

3) Kai Kupferschmidt (2020). Mutant coronavirus in the United Kingdom sets off alarms, but its importance remains unclear © 2020 American Association for the Advancement of Science, December 20, 2020 Open Access:

https://www.sciencemag.org/news/2020/12/mutant-coronavirus-united-kingdom-sets-alarms-its-importance-remains-unclear

4) Nick Ferrari (2020). Sage expert sets out details of the new coronavirus variant © Global 2020, Dec. 21 2020 Open Access:

https://www.lbc.co.uk/radio/presenters/nick-ferrari/sage-expert-new-covid-variant/

Yours sincerely, Bulcsu Szekely

Thanks a lot Dr. Bulcsu Szekely really thanks. Thanks for the very helpful links. I fully agree with you about that, Yes, we need more time to gather data on this new variant of virus, my sincere gratitude, Doctor.

Dear Dr. Kanaan! I am still now a Master of Science. They will not necessarily allow me to be a doctor of science due to a political hunt-down - they compete against me at LUT University!!! yours Bubu

Dear Bulcsu Szekely, but I always address everyone here with a doctor because I feel that we are a community of scholars, and I think you deserve it, and I hope that God will help you to get what you wish because you really deserve it ... Thank you very much and with my sincere gratitude. Yours Sincerely Manal

The mutation in the new virus (The mutation N501) allows it to enter the cell faster.

New Covid strain: How worried should we be? - BBC News

https://www.bbc.com/news/health-55312505

Thanks a lot Dr. Serdar Kalemci really thanks. Thanks for the very helpful link. My sincere gratitude, Doctor.

Please look at the following link....... I think it is useful update!

EXPLAINER: Are new coronavirus strains cause for concern?

December 21, 2020.

https://apnews.com/article/new-coronavirus-strain-england-explainer-74ea2d47820b8dcac02f95ad9440f533

Thanks a lot Dr. Lamia Al-Naama really thanks. Thanks for the very helpful link. My sincere gratitude, Doctor.

There is no clear-cut evidence the new variant of coronavirus - which has been detected in south-east England - is able to transmit more easily, cause more serious symptoms or render the vaccine useless .

Since November 2020, the United Kingdom (UK) has reported a rapid increase in COVID-19 cases in London and southeast England. This rapid increase in cases has been linked to a different version—or variant—of the virus that causes COVID-19 (SARS-CoV-2).

There are reports of some cases of the variant in Denmark, Australia and South Africa. However research by Nextstrain, which has been monitoring development of the virus around the globe, has suggested that the virus in South Africa, while having similar properties to the UK variant, has developed independently.

The British variant has about 20 mutations, including several that affect how the virus locks onto human cells and infects them. These mutations may allow the variant to replicate and transmit more efficiently, said Muge Cevik, an infectious disease expert at the University of St. Andrews in Scotland .

SARS-CoV-2 RNA has also been detected in other biological samples, including the urine and feces of some patients. One study found viable SARS-CoV-2 in the urine of one patient. Three studies have cultured SARS-CoV-2 from stool specimens. To date, however, there have been no published reports of transmission of SARS-CoV-2 through feces or urine.

Thanks a lot Dr. Kamal M Alsaad really thanks. My sincere gratitude, Doctor.

This is another link

What you need to know about the new variant of coronavirus in the UK

Read more: https://www.newscientist.com/article/2263077-what-you-need-to-know-about-the-new-variant-of-coronavirus-in-the-uk/#ixzz6hT5doI6O

Dear I'm just wondering about the previous strains of covid, is the rate of spread and contagiousness is like arithmetical progression in this virus???

Thanks a lot Dr. Lamia Al-Naama really thanks. Thanks for the very helpful link. My sincere gratitude, Doctor.

Thanks a lot Dr. Aseel Hatif really thanks. Infection rates are lower in previous strains, possibly due to mutations that occurred in the spike protein, which make the virus more attached to cells and spread faster. With my sincere gratitude, Doctor.

I think it's the genetic mutation to COVID 19, and this habit of wandering makes the virus more common But it is less fata

Thanks a lot Dr. Aqeel yousif Alshukri really thanks. We hope so Doctor. My sincere gratitude, Doctor

B.1.1.7, as it is known, has 17 mutations compared with the original SARS-CoV-2 virus first discovered in Wuhan, China, including eight that may change the shape of the outer spike protein. Many of these mutations have been found before, but to have so many in a single virus is unusual. It was first sequenced in the UK on 20 September, but only caught the attention of scientists on 8 December, when they were looking for reasons for the rapid growth of cases in south-east England. On 14 December, the UK’s health minister, Matt Hancock, told parliament that a new variant that seems to spread faster had been identified. https://www.newscientist.com/article/2263077-what-you-need-to-know-about-the-new-variant-of-coronavirus-in-the-uk/

The mutations that might change the shape of the spike protein may allow the virus to bind to receptors on human cells more strongly and thus get into cells more easily. This may increase viral replication in the upper airways – initial results suggest there are more viruses present on average in swabs from people infected with B.1.1.7 than with other variants. There are also “hints” that it is more likely to infect children, https://www.newscientist.com/article/2263077-what-you-need-to-know-about-the-new-variant-of-coronavirus-in-the-uk/

The mutation on the spike protein may enhance the virus’s ability to interact with ACE-2, giving it a growth advantage, he said. On the other hand, the spike protein is the bit of the virus that the vaccines are designed to develop antibodies against, so this mutation could impede the vaccine from doing its job. “It’s something that really does need to be monitored,” https://www.google.com/amp/s/amp.theguardian.com/world/2020/dec/20/fast-spreading-covid-variant-in-england-uk

Kindly check https://m.youtube.com/watch?v=qN3pcfXeq8w

Thanks a lot Dr. Chinaza Godswill Awuchi really thanks. Thanks for the very helpful information and links. I fully agree with you about that, Yes, possibly the mutations that occurred in the spike protein, enhance the virus’s ability to interact with ACE-2, which make the virus more attached to cells and spread faster. With my sincere gratitude, Doctor.

https://www.bbc.com/news/health-55388846

Thanks a lot Dr. Anwar A. Abdulla really thanks. Thanks for the helpful link. My sincere gratitude, Doctor.

I totally agree with Arbind K. Choudhary

Experts attributed the causes of the emerging coronavirus to mutation through new strains, to several reasons, including methods of treating patients with "Covid-19", according to the "National Geographic" website. A virologist at the University of Cambridge, Ravindra Gupta, said that there are various reasons behind the very large mutations in the "SARS-Cove 2" virus, including the treatment protocol for patients. He added: "The virus mutations are due to treatment through the plasma of sympathizers in some, and others due to the anti-viral drug remdesivir, and others because of their immunity." For his part, the lecturer specializing in infectious diseases at the University of St. Andrews, Moj Civic, said that "in the event that the causes of the transformations are proven to be treatment methods, this is a reminder to the medical community of the need to use treatment options carefully." Viruses develop once or twice a month, according to professor of microbial genomics at the University of Birmingham, Nick Lowman, but scientists have found that the Coronavirus achieves mutations at a rate of 23 times a month and faster than expected. Commenting on the new strain discovered in the United Kingdom earlier this month, Le Mans says: "This is an amazing and extraordinary discovery." The emergence of a new strain of Coronavirus, known as "N501Y" in the United Kingdom, caused a state of panic around the world. Dozens of capitals canceled flights with the country that became isolated, last Monday, while the World Health Organization confirmed that this strain is not "out of control." In the meantime, the British authorities discovered two cases of another new strain of Coronavirus known as "N439K", saying that its source was South Africa, and imposed "immediately" restrictions on travel with this country. Health Minister Matt Hancock said that the new mutated strain is "a major concern because it is more contagious and appears to have mutated more than the new strain that was discovered in the United Kingdom". Although scientists are not sure how the group of mutations appeared, the hypothesis of treating patients with chronic diseases with recovered plasma may have led to the occurrence of these mutations, especially since the continuous use of treatments increases pressure on viruses to develop themselves. Scientists say that the viral mutation has always been a regular thing, but the source of concern in the new strains is the "unprecedented" transformation of the external protrusions of the virus, which it uses to attack the body's cells. However, scientists rule out that vaccines are useless with new strains of the coronavirus, as vaccines retain their effectiveness even as the virus mutates.

https://www.alhurra.com/coronavirus/2020/12/25/

Thanks a lot Dr. Raya Al-Naimi really thanks. Thanks for your contribution and comment. My sincere gratitude, Doctor.

Thank you for the link Chinaza Godswill Awuchi

Possibility is there

Thanks a lot, Dr. Augustine Senanu Kukah and Dr. Zahid Fazal really thanks. Thanks for your contributions and comments. My sincere gratitude, Doctors.

I dont beleive ....now all strains under control

Dear Dr. Manal Hadi Kanaan , based on the current situation, it seems to me...the spread can be more attributed to (careless) human behaviour and can not be attributed to virus behaviour. Warm regards Yoganandan

This informative editorial on SARS-CoV-2 Viral variants in JAMA sheds more light on this topic.

Article SARS-CoV-2 Viral Variants—Tackling a Moving Target

Dear Dr. M.K. Tripathi , Dr. Yoganandan G. and Dr. Muhammad Yousuf really thanks. Thanks for your contributions and comments. My sincere gratitude, Doctors.

Global reports say that the infection rate has come down. We need to maintain it. Recently a report says that the maximum populations are not maintaining restrictions that WHO and local Governments have implemented earlier. I think we need to use musk and physical distancing. The other thing is vaccination. Initially, there was no vaccine. Now we have several and a couple of brands are claiming that their products have the efficacy to resist this variant.