How do we prevent hindrence of scientific progress by patent issues?

Currently the technology of gene editing CRISP-Cas9 is being addressed in counts over the matter who owns the patents. As a result progress by making use of this technology may be hampered....

31 December 2016 3,523 2 View

Cancer a mere matter of luck? Or is there something under-appreciated?

31 December 2014 692 88 View

What are the criteria to be eligible for proton beam therapy?

Ashya King is now finally receiving the treatment his parents were after. But not before they had to jump through legal hoops, like taking their child from his hospital to Spain and being taken...

08 September 2014 8,198 3 View

Is an intact immune system essential for adequate cancer treatment?

In another thread (http://tinyurl.com/k2em55e) we learn that there are two camps on approaches to cancer therapy: one is for targeted therapy, the other is phenotype-oriented. But both camps...

05 June 2014 787 4 View

Is the efficacy of chemotherapy a biological enigma?

Based on other discussions, it appears that former claims of efficacy (no matter what therapy) are disputed based on unclear statistic underpinning. One conclusion was that a clinical trial needs...

04 May 2014 5,321 12 View

Which platform gives the best overview on protein biomarkers?

Many genes and their proteins are indicated in one disease or the other, either by expression changes, or by post-translational modifications. I would like to see an overview of where we currently...

05 June 2013 4,445 4 View

How are antibody vendors perceived by researchers these days?

After a debate of several years on the robustness of commercial antibodies through multiple publications (see latest reviews in our blog...

01 January 1970 5,803 0 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

No title

02 March 2021 3,060 3 View

How to code open-ended questions in SPSS?

Hello all, In SPSS I am going to code 2 open-ended questions. I have already read all the answers and I made a list of the most important categories to which I can code the answers. This question...

02 March 2021 1,757 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View