Genome duplication and gene-family evolution: the case of three ...
https://www.ncbi.nlm.nih.gov/pubmed/18573316 -- A De Grassi - 2008
Both biotic and abiotic stress may results in gene duplication!
Check the link below:
Article Gene Duplicates: from origins to implications for plant evolution
For a very long time now, Colchicine has been used to induce diploidy in higher plants, doubling the whole genome. It does not seem to do so in mammalian tissue, as evidenced by its common use as a gout medicine in humans. I have never had time to follow up on this and would be curious to hear what it would do to a yeast. Here is an example of a relevant plant publication.
http://scholar.lib.vt.edu/ejournals/JARS/v44n3/v44n3-paden.htm
Perhaps looking up its mode of action would give you a lead as to what kind of stress would cause such a thing in nature. Domestic wheat seems to have duplicated its genome naturally on occasion and includes several ploidy varietys (species?). I hope this helps.
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