I have 4 conditions with 2 treatments (FP and LP) and are called FP-T1, LP-T1, FP-T2 and LP-T2. I have solvent controls maintained for both these conditions since the doses of solvents for FP and LP are very different and the solvent itself has a known mild effect on the cells. These solvent controls are called FP-SC-T1, LP-SC-T1, FP-SC-T2 and LP-SC-T2. I have raw counts of the RNA sequencing results for all these 8 conditions. How should I proceed with this data and negate the effect on solvent from their respective treatment groups? Thank you for the help.