Does anyone know what the biological function of hydroxypyruvate isomerase (Hyi) is in animal cells? I know that it catalyses the chemical reaction of hydroxypyruvate to 2-hydroxy-3-oxopropanoate, but what is the physiological function/role of this in animals? ie. What metabolic pathway(s) is it involved in and when might the cell require its expression?
The only thing I know about it that it might be essential gene for the production of serine as Tartronate semialdehyde and hydroxypyruvate are precursors. It seems it is a widespread across the tree of life.
Dear Adam E Hall,
Hope the following links will be useful:
http://www.genecards.org/cgi-bin/carddisp.pl?gene=HYI
http://www.uniprot.org/uniprot/Q5T013
HYI (Hydroxypyruvate Isomerase (Putative)) is a Protein Coding gene. Among its related pathways are Metabolism and Glyoxylate and dicarboxylate metabolism.
hi see this link
https://academic.oup.com/jxb/.../3/.../Engineering-photosynthesis-in-plants-and-synthetic
https://www.ncbi.nlm.nih.gov › NCBI › Literature ›
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