It is thought that angiontension converting enzyme -2 (responsible for degradation of angiotensin II) is required for cell entry of SARS-2(novel coronavirus COVID 19). ACE inhibitors are not thought to inhibit ACE-2 and so far no studies I can find that ACE inhibitors would help transmission of COVID. Is there any known or proposed mechanism as to why patients with underlying heart problems carry greatest risk of death from COVID-19?