I want to deacetylate the chitosan in sodium hydroxide (50 % w/w) solution. Does that mean 50 g NaOH in 50 mL of distilled water? What should be the appropriate time and temperature for the complete process? There are different temperatures and times are reported in literature.
Thank you for your help!
The deacetylation of chitosan in sodium hydroxide (NaOH) is a chemical process used to modify the properties of chitosan, a biopolymer derived from chitin. The protocol for deacetylation of chitosan in NaOH typically involves the following steps:
Rodolfo Bolaños Barrera thank you for providing the complete information about the protocol.
I have read and saw that condensor is attached to the flask while heating the chitosan in NaOH solution for 7-8 hr. if temperature is 120 degrees then it is conducted for 2 h and if temperature is 90-100 the process is for 6-10 hr
Mostly 50% NaOH is used for the deacetylation.
The reaction time and the temprature depends on the level of deacetylation that you would like to achieve. If you let your mixture react longer then the level of deacetylation will be higher.
You might need to experiment a bit till you get a product that has the desired characteristics. Or if you have a procedure for a product with the desired characteristics in the literature then you can simply follow that and get some good results.
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