There are a multiplictiy of publications on plate reader approaches, e.g.

Hakkim, A. et al. (2010): Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis, Proceedings of the National Academy of Sciences 107 (21), S. 9813–9818.

Parker, H. et al. (2012): Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide, Journal of Leukocyte Biology 91 (3), p. 369–376.

Fuchs, T. A. et al. (2007): Novel cell death program leads to neutrophil extracellular traps. In: J. Cell Biol. 176 (2), p. 231–241.

Maybe me or someone else could be more of help if you tell more precisely what you want away from the common approach.

THANKS !!

Try the Cayman NETs quantification kit, worked for me!