Dear Dr. Mohsin Abdullah Al-Shammari,
bioactive glass first synthesized by Hench and associates is the generic name of a class of amorphous material covering a wide range of bioactivity arising from variation of the chemical composition. The most common components of bioactive glass are SiO2, CaO, Na2O and P2O3.
The SiO2 content determines the chemical stability and the bioactivity of the Glass. Melt-derived glass which has SiO2 content larger than 60 wt% is chemically stable and hence is not bioactive. Bioactive glass with 45 wt% SiO2 is characterized by a high rate of bioactivity in that a high interfacial bond strength is established within 30 days.
Many additives including MgO, K2O, B2O3, Al2O3, Zr2O3, CaF2 and Ta2=5 can be added to bioactive glass in order to improve its mechanical and thermal properties or in order to enhance the workability range. However, a boundary conditions that limits themodification of the composition of bioactive glassi s the bioactivity property.
For more details, please see the source:
-COMPREHENSIVE BIOMATERIALS II Vol. 1 : Metallic Ceramic, and Polymeric Biomaterials
Editor Paul Ducheyne, Elsevier, ISBN: 978-0-08-100691-7 (2017)
Best regards, Pierluigi Traverso
Dear Dr. Mohsin Abdullah Al-Shammari,
bioactive glass first synthesized by Hench and associates is the generic name of a class of amorphous material covering a wide range of bioactivity arising from variation of the chemical composition. The most common components of bioactive glass are SiO2, CaO, Na2O and P2O3.
The SiO2 content determines the chemical stability and the bioactivity of the Glass. Melt-derived glass which has SiO2 content larger than 60 wt% is chemically stable and hence is not bioactive. Bioactive glass with 45 wt% SiO2 is characterized by a high rate of bioactivity in that a high interfacial bond strength is established within 30 days.
Many additives including MgO, K2O, B2O3, Al2O3, Zr2O3, CaF2 and Ta2=5 can be added to bioactive glass in order to improve its mechanical and thermal properties or in order to enhance the workability range. However, a boundary conditions that limits themodification of the composition of bioactive glassi s the bioactivity property.
For more details, please see the source:
-COMPREHENSIVE BIOMATERIALS II Vol. 1 : Metallic Ceramic, and Polymeric Biomaterials
Editor Paul Ducheyne, Elsevier, ISBN: 978-0-08-100691-7 (2017)
Best regards, Pierluigi Traverso
Paul Ducheyne, Kevin Healy, Dietmar W. Hutmacher - 2015 - Technology & Engineering
Dear all, I just support the nice details given by Dr. Pierluigi Traverso, by the attached document. My Regards
Dear Mr. Abdelkader BOUAZIZ , thanks so much for your advice.
Dear Mohsin Abdullah;
The most studied and used bioactive glasses are mainly composed of oxides of silicon (SiO2), sodium (Na2O), calcium (CaO) and phosphorus (P2O5). In classical glass theory, the first two oxides are network formers while the last two are modifiers. The exact role of phosphorus oxide is actually more complex. Compared to traditional glass compositions (soda-lime glasses), bioactive compositions have certain distinguishing features: moderate SiO2 content (< 60%); high Na2O and CaO content; high CaO/P2O5 ratio. The most used and most bioactive glass is the 45S5 bioglass (composed in % by weight of 45% SiO2, 24.5% NaO2, 24.5% CaO and 6% P2O5). This bioglass is classified over the whole range of bioactive materials in class A, which corresponds to the highest bioactivity index. This bioactivity is due to the capacity of the bioactive glasses to when immersed in the physiological environment, to form carbonated hydroxyapatite (CHA). This CHA layer allows a chemical bonding of the implant to the bone in about 12 hours. The bioactivity of 45S5 bioglass gives it osteoconduction, osteostimulation and resorption properties.
With my best regards
I think the following link might be helpful to you with my compliments.
Article Bioactive Glass in Tissue Engineering
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