Several vacuum pumps are developed for creating vacuum in laboratory and also measuring gauge are developed based on physical phenomenon.How far we reached near perfect vacuum in laboratory.
Ion gauges (cold cathode, hot cathode) can get down to 10E-10 and 10E-11 torr. Take a look at UHV (Ultra-high Vacuum) manufacturers literatures, e.g. Perkin Elmer, Anton Parr, etc.