What is the IC50 of Tamoxifen for inhibiting estrogen receptor in MCF-7 and T47D cell lines?
For MCF7 I found IC50 of 4.506 µg/mL
https://jumdjournal.net/article/view/2393
but for T47D lines might look at this one Article Genetic ablation of pregnancy zone protein promotes breast c...
I was thinking, is not IC50 usually empirically determined for each cell line?
Recently, I established the mechatronics club at the college of engineering in our campus. In addition, I visited high school students in order to establish engineering club. Also, I hosted middle...
18 April 2020 526 93 View
Beside classroom lectures, I explored other methods of research activities such as: Field Trips: I accompanied 12 students from Automatic Control course to visit a Steel Company. In this trip, the...
26 March 2020 1,788 94 View
We have been working on breast MDA-MB-453 cells. We found that hormonal treatment increases expression of three genes: Slug, RGS2 (regulator of G protein signaling 2), and MMP-13. When cell were...
03 April 2018 7,369 5 View
Dear my friendsWe are a scientific group working with GC.MS system . We pleased to make a scientific co operations with any one who interested to analysis his samples on itThanksDr.mamoun
21 December 2014 2,279 2 View
I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...
03 March 2021 4,116 4 View
02 March 2021 3,060 3 View
Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...
02 March 2021 3,024 2 View
02 March 2021 7,082 3 View
Hi. I am doing non linear FE analysis using a new material beam under flexural 2 point loading using ANSYS. I have defined a bilinear material model. The solution has converged. In results I am...
01 March 2021 9,911 3 View
Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...
01 March 2021 3,867 3 View
We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...
01 March 2021 3,355 3 View
I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....
01 March 2021 3,607 3 View
Hello, Could you please share any interesting research explaining how to choose the number of hidden layers and nodes per layer in case of regression problems using ANN? Thank you, any help would...
01 March 2021 6,200 3 View
Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...
01 March 2021 8,169 2 View