How to perform R^2 and p-value in Pcoa Plot?

Dear All, I have the weighted and unweighted distance matrix output file from QIIME2. I would like to find the Community structure differed significantly between the groups according to the beta...

08 September 2019 3,016 3 View

How to import biom format obtained from QIIME2 into Tax4Fun?

Hi All, Ive tried to run tax4fun using biom file obtained from qiime2 platform. Ive attached my text file coverted from biom format. How do I rectify this error?...

06 July 2019 1,014 1 View

Clarification on Proteome Discoverer Output file?

We have done LC/MS-MS analysis and executed Proteome Discoverer for identification of proteins. In the output, I found there are many proteins fragments and also found that one protein present...

10 November 2018 4,299 5 View

How to find significantly expressed proteins from proteome discoverer ??

Dear all, i am a new baby in the field of proteomic. Now I have the multiconcencous results obtained from proteome discoverer. I need to find the significantly expressed proteins between three...

05 June 2018 3,250 2 View

How to assign Taxonomic Classification for OTU tables?

I am new to metagenomics. I downloaded a 16s rRNA data from sra and generated OTU table using USEARCH. How to assign Taxonomic classification to OTU table. I tried with the following...

01 February 2018 2,957 2 View

What is skipped exon annotations file?

07 August 2017 7,829 1 View

How to convert .maegz format to PDB format ?

I have a docking results of one protein and one ligand in .maegz format. I need to visualise this result in discovery studio visualiser. But DS visualizer doesn't support .maegz format. So how to...

02 March 2017 6,190 6 View

How to get the complete graph after extened the nanoseconds from 10-20?

I have extended the simulation from 10ns to 20ns using .cpt file during molecular dynamics run,when i am trying to analyze the result i am getting the graph only from 10ns to 20ns instead of...

01 February 2017 2,464 3 View

Is there any idea for creating a perl module

I have assigned to create a small Perl module which can be using for bioinformatics and bio statistics. I have searched for many ideas. But almost all ideas are already there in CPAN. Can anyone...

09 October 2016 7,499 4 View

Summer Internship for M.tech Bioinformatics with 2 months

I am currently pursuing my M.tech Bioinformatics. I am seeking for good internship where i can enhance my Bioinformatics skills. Ive come across so many internship. But i dont know what will be...

07 August 2016 8,024 2 View

How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

Does any one know how i can prepare liver tissue with transmission electron microscope with good fixation?

i have problem in preparation of liver tissue with bad cell organelles and how i can adjust osmolarity

03 March 2021 8,890 1 View

Waters 2707 HPLC autosampler problem?

I am using a 2707 waters HPLC device. When I try to inject a sample, it says missing plate or rack. I changed the needle and calibrated its position but I still get the same problem. I even get...

02 March 2021 1,408 1 View

Gel electrophoresis result for total RNA samples, 1.5 Agarose gel was used, How to improve the integrity of RNA?

Gel electrophoresis, RNA degradation, RNA extraction from fresh tissue

02 March 2021 5,433 5 View

Why almost every element would be metallized in sufficiently high pressure and low temperature?

(This statement is from wikipedia, BTW). What is so special about metallic bond that is limiting high-P low-T state of a matter (as long as individual atoms exist, not white dwarf of neutron star...

02 March 2021 3,309 2 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

I have designed reflectarray element and feeding it though Horn Antenna on HFSS. After full wave simulation, I am not getting desired results?

I have designed reflectarray element to generate OAM beams at 5.8GHz and feeding it though Horn Antenna on HFSS. After full wave simulation, i am not getting desired results i.e Radiation pattern...

01 March 2021 9,701 5 View