How is the long-term impact of these medications on the quality and duration of slow-wave sleep in terms of their alterations on the stability of dopaminergic and serotonergic activity in the brain? My hypothesis is that it could be negative or detrimental...
Your hypothesis coincides with the opinion of many experienced somnologists. Various neurotransmitter systems (serotonin, dopamine, glycine, GABA, glutamate, acetylcholine, allenalin, purines, gaseous mediators ...) are involved in the control of the phases of sleep, as well as sleep and wakefulness. Modern drugs for the regulation of sleep phases act on two or three neurotransmitter mechanisms. The other neurotransmitters of "sleep" begin to show sometimes unpredictable reactions to such "interference from outside." Ultimately, instead of correcting the phases of sleep, we observe how the dependence on drugs and the disturbance of biorhythms develop.
- Badges
- Science topic