In three dimensional structure along with alpha helix, beta sheet, beta turns and other non co valent interactions, the protein folds to form motifs but how it is different from domain?
Motifs are structural characteristics and domains are functional regions (not necessarily related to size). In a protein, a particular arrangement of amino acids or secondary structure that can be found in other proteins (not necessarily evolutionarily related) can be called a motif. If that particular arrangement is related to some function (DNA or protein binding, catalytic, etc.) then it is a domain. For example, the leucine zipper motif is usually found as part of a dimerization domain in many transcription factors.
Google is your friend: http://stanxterm.aecom.yu.edu/wiki/index.php?page=Protein_domains_and_motifs
Put very simply, a domain can be made up of one or more well characterised motifs which usually occur together and suggest a putative function.
Motifs are structural characteristics and domains are functional regions (not necessarily related to size). In a protein, a particular arrangement of amino acids or secondary structure that can be found in other proteins (not necessarily evolutionarily related) can be called a motif. If that particular arrangement is related to some function (DNA or protein binding, catalytic, etc.) then it is a domain. For example, the leucine zipper motif is usually found as part of a dimerization domain in many transcription factors.
This is my understanding. Both are supersecondary structures, i.e. Made of multiple secondary structures. Domains are more complex and larger. They are compact structures of multiple secondary structures that are at a distance from each other. On the other hand, motifs can be structural or sequence. Sequence motifs share certain sequence of amino acids. Structural motifs are made of multiple secondary structures that are sequential to each other within the primary structure of a protein (e.g. Helix-loop-helix) and not separated by a random structure. Domains can contain a motif. Both domains and motifs can be functional or just mere structural.
Domains are stable,folded, complexed and larger and emerge from the motif while motifs are stable speciall elements of secondaray structure and connection between them.
Motifs are structural characteristics and domains are functional regions
Can you determine allele size frequency or allele size range from SSR sequence data
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