Hi there,

Let us assume we have two patients one of whom is internally bleeding and the bleeding is hidden: vital signs are not changing. In other words, she/he is experiencing occult hemorrhage. It is clear that the sooner we detect that patient the better we are with regards to their treatment. My research question is that, on average, what is the maximum time we have to detect the patient? I mean if X minutes has passed, and if we found out that this patient is bleeding, we are not confident that the treatment helps.

Basically, I want to make a trade-off between the delay we can make in the treatment, the false positive cost of treatment, and the false negative cost of treatment. I assume that the resources are limited so we can only detect one patient here.

Can anyone please help me to find a related paper or has some ideas about the above questions? I tried my best to find something out there to no avail.