IL-17 Production in Patients with American Cutaneous Leishmaniasis
Olívia Bacellar,1 Daniela Faria,2 Márcia Nascimento,1 Thiago M. Cardoso,1 Kenneth J. Gollob,3 Walderez O. Dutra,2Phillip Scott,4 and Edgar M. Carvalho1
Abstract
Interleukin 17 (IL-17) plays a critical role in inflammation and autoimmunity. Very little is known about IL-17 in protozoa infection. Here we show that lymphocytes from mucosal leishmaniasis (ML) and cutaneous leishmaniasis (CL) produce higher levels of IL-17 than uninfected controls (UC) (p