There is currently no evidence that any treatment applied to people with a complete spinal cord transection leads to restored neurological function. The diagnosis of a complete transection is not so easy to establish unless it is very apparent on a sagittal MRI. In animal experiments, the complete transection model has been popular as an unequivocal test of axonal regeneration. There have been several publications that have indicated that a regenerative effect of cells/glial/stem combined with neurotrophic factors and biomatrix (fibrinogen, etc.) or guidance channels can support some extent of axonal regeneration. However, not all of the studies can be replicated and sometimes the regeneration distance is so little (e.g. 50 microns) that it may not be meaningful in people.