Since  direct measurement of the absorbed dose to target organs   from nuclear medicine procedures is rarely possible,  most estimates rely on the  Monte Carlo simulation or numerical calculation based on indirect measurements/radiopharmaceutical data.

Here in the  US MIRD method  has been  developed by Medical Internal Radiation Dose Committee (http://www.snmmi.org/AboutSNMMI/CommitteeContent.aspx?ItemNumber=12475)  that allows the calculation of dose to target organs, see e.g. http://ozradonc.wikidot.com/methods-of-dose-estimation,

http://www.arpapress.com/Volumes/Vol11Issue1/IJRRAS_11_1_17.pdf,

you can find more references on the MIRD webpage under MIRD publications.

Dedicated MIRDose software is developed by M.G. Stabin that simplifies the calculations.

(M.G. Stabin, and G.D. Flux. "Internal Dosimetry as a Tool for Radiation Protection of the Patient in Nuclear Medicine". Biomedical Imaging and Intervention Journal, 2007; 3(2) 28)

http://www.snmmi.org/AboutSNMMI/CommitteeContent.aspx?ItemNumber=12475

Have a look at ICRP 53 with all addendums. You will find a lot of informations.

The best method would be the use of in-vivo

Dear Vaidehi,

your proposal will fail if you look for the location of metastsis etc.

could you please give some more hints and explanations.

Hi

The gate Montecarlo code has a reliable method for internal dosimetry in nuclear medicine.

olinda is best option for that