What is considered a good binding affinity energy value between macromolecules?

Hi everyone, Does exist any threshold for binding affinity value between macromolecules? E.g. Any value lower than -5.0 Kcal/Mol..... How to determine that the binding affinity among different...

22 September 2020 4,329 3 View

Means and SDs for proportions - How to proceed when we need the inverse data?

Hello all, I have a tricky situation here. I need a % and SDs of drug-negative urine tests across a methamphetamine study for a meta-analysis. However, the study brings the % and SDs of...

30 March 2020 9,494 3 View

Meta-analysis - what if we have two treatment groups?

Dear all, I'm writing a meta-analysis about treatment of stimulants use disorders. I am pooling data from RCTs using a certain class of medications. However, some of the described studies used...

03 July 2019 5,014 3 View

How do I get RRRs rather than ORs from Multinomial Regression on SAS?

I have run a proc surveylogistic model using link=glogit on sas. The idea is to run a multinomial regression model. However, whenever I run the model with it covariates, SAS provides an output...

18 January 2019 8,977 6 View

What is the best way to combine/merge/concat datasets of different size?

I want to know if have some way to combine datasets with a different number of instances into one so that the final dataset is not biased to larger datasets. For instance: we have the dataset A,...

26 September 2017 9,640 4 View

Can anyone indicate me protocols, questionnaires and tree decisions regarding environmental risk assessment of microorganisms?

environmental risk assessment quantitative risk assessment microbial risk assessment ecologial risk assessment enviromental risk assessment of microorganisms

19 March 2017 2,056 3 View

Is there any way to obtain the old 1980's software called Javelin?

Built by the creators of Visicalc and a competitor of spreadsheet software

03 February 2016 4,829 3 View

How can I dissolve commercially available LDL lyophilised powder?

I have tried PBS (pH 7.4), tris-glycine buffer (7.4) and I still can't get a full dissolution of LDL.

17 January 2016 3,820 3 View

What's the current state-of-art ensemble predictors combination?

13 October 2015 1,311 3 View

Does the laser used in physical therapy entails changes in skeletal muscle in patients with cancer?

06 August 2014 7,691 3 View

How can I do the bang's blinding index and james blinding index?

Hi! I would like to know with which statistical software the bang blinding index and the James blinding index and how to do it. Thanks

09 December 2020 1,363 2 View

How Blind and Visually Impaired can Navigate in indoor areas?

Dear all, I am thinking to develop solutions for blind people to navigate and positioning themselves in indoor areas such as malls, hospitals, etc. I am thinking about the tool or device that can...

18 September 2020 8,671 7 View

Mention the name of parasitic worm that causes river blindness?

mention the name of parasitic worm that causes river blindness?

04 July 2020 6,066 8 View

How to model blind bolts in ABAQUS?

I am trying to simulate a beam-column connection using blind bolts. but I am not getting an idea to model blind bolts in Abaqus. please give me some idea of modelling. thanks in advance

05 February 2020 8,916 3 View

Newer is always better in our bibliographies ?

It is common, in the so-called "hard" sciences, that recent bibliographic sources are privileged compared to sources dating back several years. This practice is consistent with the notion of the...

05 June 2019 908 4 View

As a reviewer for journal manuscripts, what type of reviewing process you prefer? Single blind, Double blind or Open review and why?

Journals are different in their reviewing process in terms of the information given about the reviewers and authors. There are three major types Single blind in which the reviewers know the...

18 April 2019 6,187 21 View

What is the configuration file for blind docking using PyRx for multiple ligands?

I am trying to run blind docking with multiple ligands and one macromolecule using PyRx but somehow i am getting poor binding affinities. What is the configuration file for blind docking in PyRx...

03 April 2019 9,112 4 View

I am legally blind and request help finding articles from 2013 forward on the social media effect on f2f interactio n?

see question above

03 April 2019 922 1 View

What is wrong about double blind peer review?

Double blind reviewing may serve as guidelines for the authors to improve their submission. But many researchers say that double blind review involves some high-profile experts who are...

03 April 2019 5,143 6 View

What is the configuration file for blind docking using PyRx for multiple ligands?

I am trying to run blind docking with multiple ligands and one macromolecule using PyRx but somehow i am getting poor binding affinities. What is the configuration file for blind docking in PyRx...

01 April 2019 2,132 3 View