What is the best animal model [rats?] for induced AMD and to evaluate potential treatment?
Hi
In related to first question, the following article may be helpful.
Regards
Many thanks!
The best model will be primate monkey
We published a protocol model of CNV in mouse which mimics AMD.
https://www.researchgate.net/publication/258055788_Laser-induced_choroidal_neovascularization_model_to_study_age-related_macular_degeneration_in_mice
This model is rapid, reproducible and ethically acceptable in contrary to primate model.
Article Laser-Induced choroidal neovascularization model to study ag...
Many thanks, Does the age of the mice relevant?
It's better with mice between 6-8 weeks. But slightly older is also good.
But your control group should absolutely has the same age.
great thanks
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