Hello,
I am working on a medicinal effects of some compounds on CCl4 induced hepatitis in mice.
I used single dose of CCl4 1 ml/kg (1:2) in corn oil but its not causing inflammation and necrosis after 24, 48 and 72 hours.
Therefore, I am looking for an appropriate dose of CCl4 which can cause acute hepatitis and I also want to know how long it will take to develop the above stated model?
Need help in this regards.
Thanks in advance!