I am planning to run a kinetic CIA experiment using male DBA1/J mice and I would like to see change in expression of gene of interest at various stages of disease. I have been reading about the appropriate antigen for induction of disease and found that people use both bovine CII and chicken CII for immunizing this strain. Could anyone suggest if one is better than the other or if it is context dependent. Please suggest appropriate concentration for induction and booster, as well.

Thanks in advance!

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