Hello S. Ranga,

You can see the following articles:

https://www.researchgate.net/publication/314108392_Preparation_and_characterization_of_chitosan-bentonite_nanocomposite_films_for_wound_healing_application

https://www.google.com/amp/s/www.researchgate.net/publication/330330013_Development_and_in_vitro_characterization_of_chitosanstarchhalloysite_nanotubes_ternary_nanocomposite_films/amp

that is depend on the materials of hydrogel. if your hydrogel based on proteins you can utilize pepsin or trypsin

@Tamer M Tamer

Thank you sir.