Synovial fluid is normally a thick, straw-colored liquid found in small amounts in joints, bursae (fluid-filled sacs in the joints), and tendon sheaths.
I don't think it is practical to replace synovial fluid. Connective tissue spaces generate their own fluid constantly. If you put anything in it will diffuse out very rapidly. I guess the question is why one would want to replace the natural fluid?
You need to think about composition synovial fluid which is far complicated than one thinks, not only viscosity or colour. It is impossible to replace synovial fluid. I agree with Jonathan
Synovial fluid is of unique composition and also differs from time to time according to the conditions that exists within the joint. It is not possible to replace the qualities and properties that this fluid has, as already mentioned above.
Synovial fluid (SF) is a plasma dialysate modified by constituents secreted by the joint tissues. The major difference between synovial fluid and other body fluids derived from plasma is the high content of hyaluronic acid (Hyaluronate) in SF. The proteins of coagulation are not found in normal synovial fluid, while proteins of the plasmin system may be found in variable quantities. To date I am not aware of a practical SF replacement. For osteoarthritis treatment viscosupplementation based on doses of hyaluronic acid that are injected into the knee but their long-term efficacy remains uncertain.
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