Recently I had the experience of seeing a 70 year old lady being followed up as Glaucoma suspect based on a large cup disc ratio with normal IOP (consistently
I agree with Dr. Kara that RNFL defects are expected to be same in glaucoma. The nerve fibers in glaucoma are always destroyed in an orderly fashion starting with the peripheral fibers and ending with the central. Nerve fibers are never destroyed haphazardly or other way around in glaucoma. If nerve fibers wouldn't being destroyed in an orderly fashion then the role of perimetry in glaucoma would be meaningless. If the nerve fibers are being destroyed in an orderly fashion the we should expect the mechanism for their destruction to be an orderly one too. Finding that mechanism may solve the mystery of glaucoma.