I am looking at alternative splicing in mouse mRNA and would like to identify if there are any heterogeneous nuclear ribonucleoproteins (hnRNPs) binding sites that influence the splicing events between consecutive exons. Similar to ESE finder that would list exon splice enhancer binding sites and SR proteins involved in it, I am interested in knowing the exon splice suppressor binding sites (ESS) and the hnRNPs involved in it. Are there any bioinformatics tools or a database that could help me further?
Hi Prashanth,
I don't know for tools since ESE finger do a particularly good job for that, but you'll find a complete database at uniprot or better at EBI for hnRNPs (https://www.ebi.ac.uk/ena/data/search?query=HNRNP).
fred
Thanks Frederic Lepretre for the link. I will give it a try.