House hold contacts exposed to TB index cases in high TB endemic regions are at high risk for development of TB infection. TNF is a key cytokine, concentration which around the granuloma determines latency and reactivation. Is TNF a marker of disease progression. Can TNF therapy be used to sustain latency?
Adiwirawan Mardjuadi
NOt easy to use anti TNF a particularly some products because not only think about TBC in the lungs but the most serius cases that I have experiences that was TBC menginitis-encephalitis with further consequences hydrocephalus. And keep in mind eventually drug resistenst and and using injections temporary streptomycine injection beside other tuberculostatica
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