Aliabbas A Husain

7 Questions 11 Answers 0 Followers

Questions related from Aliabbas A Husain

Does Bacterial CFU counts in lungs should always corresponds to antigen and antibodies load in homogenates ?

We basically did infection modelling of TB in mice using clinical strains. we estimated bacterial load at 30 and 50 days post infection, Although CFU tires were evident at both time periods, we...

02 June 2016 4,417 3 View

How can one identify individual's exposure to environmental mycobacteria ?

NTMs exposure have been long postulated to have a mediating effect on protective efficacy of BCG vaccine in TB endemic countries like India.how can we identify such exposure? Are there any ways...

01 December 2015 3,449 9 View

Can BCG be used as a therapeutic vaccine ? Can booster shots be used ?

Very rare studies are reported that have investigated role of BCG as therapeutic vaccine after TB infection. Can Single or booster dose of BCG be used as therapeutic vaccine alone with drug...

27 November 2015 2,361 6 View

How can I measure the concentration of TB drugs in organs of mice after chemotherapy? what is the ideal time after therapy to study concentration?

I am studying efficacy of TB drugs to disseminate in various organs after drug administration either orally or via IV route. Main aim is to study how much concentration actually reaches the...

03 July 2015 9,346 3 View

What are treatment regimes for Household contacts of TB cases in high TB endemic zones?

House hold contacts exposed to TB index cases in high TB endemic regions are at high risk for development of TB infection. TNF is a key cytokine, concentration which around the granuloma...

05 February 2015 1,977 1 View

What is the optimum time point for estimating Lung bacterial load after Subcutaneous MTB infection in mice. Can it be estimated at 30 days?

We have used subcutaneous route for MTB infection in mice. We have observed lung bacilli burden at 30 days after infection. I just want to know any supplementary evidence to support my result.

12 January 2015 3,950 10 View

Is there any other established protocol for eluting proteins apart from electroelution?

We are currently identifying proteomic markers in different strains of M. tuberculosis isolated from sputum and CSF samples. Is there any other established protocol for eluting proteins apart from...

26 March 2014 4,218 1 View