I'd come across a paper using R package edgeR for the same purpose.

As an alternative, you may try this

http://bioinfo.cipf.es/noiseq/doku.php?id=start

Hi,

There are many such as https://www.mirnet.ca/

Also you can use some package in R such as EdgeR or Deseq2 to perform DE analyses.

Analyzing through R (through RStudio) would definitely the best idea - it requires just a bit of work to get in, but worth to do.

After having the Differential Analysis values (DE = log2(expression/ctrl)), I would suggest miRViz, which we recently built, to interpret the dataset:

http://mirviz.prabi.fr/

quick video tutorial: https://www.youtube.com/watch?v=vrwB1hbcjyQ

bioRxiv: https://www.biorxiv.org/content/10.1101/813550v1

MiRNet is great too, and complementary to miRViz: https://www.mirnet.ca/miRNet/home.xhtml

Both would be useful for you. No need for computational skills. I would suggest first miRViz, and then miRNet.

'hope this will help you.