I have the sequence of an antibody and would like to build a decent homology structural model.
Thank you.
Hello Doc you can use discovery studio for antibody homology modelling it is a commercial software. If you would like to use it our lab has the licence for it you can contact us for the same
Doc r u asking me to model the antibody if so ya i can do it for you
Thank you Usha. I did modeling for antibody structure and refined the loops as well to get decent rmsd deviation comparable to original crystal structure.
that nice to hear then your job is done however also check for ramachandran plot for the modelled protein since it is one of the important validation process for publication
Thank you. Yes. I refined the model and validated with procheck program and i did not see any abnormal torsional angles in the model. Also I compared to orginal model and observed rmsd of 0.7 A.
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