What are the physiological indications through which I can study the effectiveness of using the immunotherapy in the patients with lung cancer?

01 January 1970 1 8K Report

I mean, which physiological or immunological parameters/markers that I need to study to know the effect of using immunotherapy in the patients with lung cancer?

Any suggestion for research would be helpful?

Thanks for your time..

Rabeah Al-Temaimi

Tabarak Jalil up to my knowledge CT imaging post op or treatment is best approach to assess tumor regression. As for circulating biomarkers, I think it would be patient specific (pre treatment cancer biomarkers) and depending on targets of immunotherapy. Consult reviews of circulating biomarkers for lung cancer such as (doi: 10.1016/j.ctarc.2021.100410), and studies monitoring type of immunotherapy you are considering (Mabs, autologous immune cell transfer, vaccine, chimeric receptors..etc). Good luck

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