What are the most reliable mathematical models for determining IC₅₀ in antioxidant assays, and how do they compare in accuracy and reproducibility?

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Rich C Joseph

@Mariel G. Klanian

Thank you so much

Abdelhak Maghchiche

The most reliable mathematical models for determining IC₅₀ in antioxidant assays include logistic, Boltzmann (sigmoidal), dose-response, and asymmetric sigmoidal models. These models offer varying degrees of accuracy and reproducibility, with the asymmetric sigmoidal model often providing the most accurate results.