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My pathologist says it is seen as atypical mitotic figures and cellular nuclear features.But IHC by P63 and CK 5/6 might help is doubtful smears.
thank you
You could consider using p40. A diffuse (full layered) expression coupled with malignant features on histology favours a SCC cell from a normal keratinocyte.
I think only the basal cells shows p40 positivity in normal skin.
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