General rule,all the minerals or amino acids or vitamins if used in very high doses for a long time will lead to toxicity
In human it could lead to nausea, vomiting, drowsiness as well worsen the symptoms of liver disease, and atherosclerosis. However, the quantity present in broiler diet doesn't' usually pose a threat.
Met exceeding the dietary requirements :
Results indicated that a 10% Lys surplus, without additional Met or with a 20% Met surplus, tended to produce the highest relative weights of bursa of Fabricius.
blood glucose increased in birds fed supplemental Lys and Met.
Met and Lys surpluses had no effect on carcass traits .
Our measurements showed that Met and Lys surpluses did not affect immune responses against AI within 30 days after vaccination, responses against NDV after the second injection, and responses against SRBC. However, when broiler diets had no Met and Lys surpluses, the highest IgG2 level against AI occurred within 40 days after injection.
The methionine requirement increases by increasing the level of production capacity of the organism
The converted enzymes of D methionine to L methionine in the liver and kidneys in small chicks are low on conversion due to the lack of enzymes available to them, and since the productivity performance of the first week old broiler has an effect on the overall performance
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