What are the chemokines that attract mast cells??

08 August 2011 1 7K Report

I'm observing the recruitment of mast cell to the region which was irradiated,

but I'm not so sure which chemokines to look at, so hope can get some advise!

Hi,

You can for sure look for RANTES (CCL5), it's the main source of mast cells chemotaxis. You can also look at CCL17 (TARC) but the litterature is confusing on this one, it's an activator of mast cells, but I don't know about it's chemotaxis ability.

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