Ag nanoparticles (AgNPs) can be synthesized by various physical, chemical, photochemical, biological and green synthesis methods, when AgNPs with tailor-made sizes and shapes can be obtained. The chemical reduction of Ag+ ions from a silver salt (i.e. AgNO3) with a strong reducing agent (i.e. sodium borohydride, NaBH4) or weak reducing agent (i.e. trisodium citrate) and stabilizers in aqueous or non-aqueous solutions is the most common method. Polymers such as poly(-acrylic acid sodium salt), poly(4-styrenesulfonic acid-co-maleic acid) sodium salt, polyvinylpyrrolidone (PVP), sodium carboxymethyl cellulose (CMC), a.o. can act both as weak reducing agents and stabilizers to prevent AgNPs agglomeration and to improve their stability in colloidal suspensions. Finally, when you choose the synthesis method for AgNPs obtaining along with the desired shape, size and concentration you have to consider the practical applications where you intend to use the synthesized AgNPs.