What are the alternative methods for lyophilization of PLGA Nanoparticles?

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How to use other researchers data set for our algorithm? should i cite or get permission?

Dear friends i have a query. i have to use a data which is a real time case study done by a canadian author. he has given data in repository. my question is when i use this data how should i cite...

01 February 2021 3,603 6 View

Doubt in DFT geometry preparation?

Hi all, I am trying to perform some ab inito DFT calculations using cp2k code. I have a unit cell of 120 atoms and would like to know how to refine or reduce the number of atoms in the unit cell...

20 January 2021 6,024 3 View

Interested in being a reviewer for Scheduling-optimization-meta heuristics?

Dear fellow researchers, I need a two to three non indian reviewers for the research area of Scheduling-optimization-meta heuristics-operation research. all the journals are asking for other...

22 November 2020 9,633 5 View

How can one use Multi angle light scattering (MALS) technique for particle size, polydispersity index of drug loaded PLGA nanoparticles?

Our research team is involved in the study of drug loaded PLGA nanoparticles and nano lipid carriers (NLCs). We are planing to use Wyatt Heleos II MALS for particle size and PDI. Any insights/...

09 October 2020 4,883 4 View

What are different methods to prove a reaction mechanism?

Our team is trying to elucidate a reaction mechanism between X and Y. Both are organic compounds. What are different ways to approach to the problem. Your suggestion will be of great help.

20 September 2020 1,083 26 View

How do you exactly determine the annealing temeperature while splicing two gene sequences in the first annealing cycle of overlap extension pcr?

In OE PCR, I have to stitch two gene sequences, so the annealing temperature in the first cycle would depend on the overlap reagion between two products designed with appropriate primers or would...

14 March 2020 2,639 3 View

Upon using DMSO and betaine the bands in my NTC and my sample look different upon doing LAMP. What does that indicate?

I am trying to sort out this primer dimer (in NTC) issue for a very long time. After many of my previous trials in which NTC and my sample bands looked same, only in this trial the NTC and my...

29 May 2019 6,897 2 View

Need intepretation regarding SEM analysis of zeolites?

Hi all, Attached are SEM images of different types of zeolites (3A, 4A, 5A and 13X in that order). How do we interpret these images? I would like to see the differences in the cage structure/...

01 April 2019 7,274 7 View

Can someboday tell me, whether Cartosat DEM provides Ellipsoidal or Orthometric Height?

I wish to utilize cartosat DEM, publicly available form bhuvan site. However, I have analyzed and seen that the elevation values from cartosat DEM are very similar to ellipsoidal height of...

06 November 2018 4,682 3 View

I am working on Synechosystis PCC 6803. I have to give salt stress to my microorganism. I am using BG-11 media. How do I add salt to my culture media?

Since BG-11 media has no NaCl content in it, I might have to add NaCl separately. If I add NaCl externally, what concentration of NaCl should I consider as my control? Kindly guide me regarding...

15 September 2018 6,037 5 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View

Heat exchanger with liquid Nitrogen as coolant?

I want to cool Natural Gas from 195 Kelvin to 138 Klevin in a heat exchanger by using liquid nitrogen as the coolant medium. When entering the heat exchanger, the liquid nitrogen will have a...

01 March 2021 6,450 5 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View

Why do a weight decrease for thermal degradation in nitrogen gas condition?

Hi all The question is related to TGA(Thermogravimetric analysis). Thermal degradation easily understood but why do samples weight decrease? altough just binding is broked, the weight of...

26 February 2021 1,100 5 View